Abstract: Substantial evidence demonstrates that diet significantly impacts the prevention and management of type 2 diabetes (T2DM). However, individual responses to dietary interventions vary, necessitating the development of personalized nutritional recommendations. Ample evidence confirms that dietary approaches can achieve T2DM remission, particularly with low-energy or low-carbohydrate diets, which aid in weight loss, improve glycemic control, and consequently lead to diabetes remission. This review aims to comprehensively analyze and compare personalized and non-personalized nutritional interventions for T2DM remission. A literature search was conducted following the Academy of Nutrition and Dietetics guidelines, including clinical trials and observational studies published in the last decade. This article discusses the advantages and limitations of applying personalized nutrition in clinical practice and identifies areas requiring further research for the implementation of personalized interventions, such as cost-effectiveness and accessibility. The findings indicate that studies employing personalized nutrition consistently report higher rates of diabetes remission compared to those using non-personalized nutritional interventions.
